The Medical Biodynamics Center (MBC) is a multidisciplinary research and training center within the Department of Anesthesia, Critical Care and Pain Medicine at Massachusetts General Hospital and Harvard Medical School . We aim to foster clinical research through three strategic priorities:

Promote Multidisciplinary Research Training To complement our department’s clinical training in anesthesia, we design and provide a series of seminars and research projects focused on sleep/circadian physiology, aging research, and complex data analysis. This multidisciplinary training enhances clinicians’ research capabilities while fostering collaborations with scientists from diverse disciplines, including physics, mathematics, data science, and bioengineering.

Establish Data Infrastructure and Analysis We are developing an infrastructure to facilitate the collection and analysis of multidimensional physiological data, including motor activity, EEG, ECG, PPG, cerebral blood flow, blood pressure, and blood oxygen/CO2 levels, primarily using wearable devices. We share analytical tools and procedures developed for assessing physiological functions such as sleep, circadian rhythms, cardiovascular/cerebrovascular regulation, and brain function. This infrastructure supports protocol development, data collection, and analysis for clinical studies and research collaborations locally, nationally, and internationally.

Build a Physiological Data Repository Leveraging our department’s role in providing anesthesia services for over 50,000 procedures annually, we are establishing a comprehensive physiological data repository. We are developing systems and procedures to extract physiological and clinical data during the perioperative period, making these datasets available to researchers to advance medical knowledge and improve patient care.